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Safety boxes with "special" insertion opening for used cannulas, scalpels, butterfly systems, hoses, etc. The opening can be enlarged step by step by breaking out the caps. If the box is accidentally knocked over, the flaps can optionally be used as a locking device against falling waste. The different pull-off/turn-off devices are suitable for all common cannula types - also for insulin syringes. The wall thickness of the box is at least 1.7 mm (puncture-resistant) at each point. The box is made of environmentally friendly polypropylene. Tested according to TRBA 250, UN 3291 and ISO 23907.